Oklo Inc. (NYSE:OKLO) is one of the best AI stocks with huge upside potential. On March 9, Oklo and Centrus Energy Corporation (NYSE:LEU) announced plans to pursue a JV aimed at advancing domestic nuclear fuel services in Piketon, Ohio. The collaboration will focus on deconversion services for high-assay low-enriched uranium/HALEU, a critical step where enriched uranium is transformed into a chemical form suitable for fuel fabrication.

By establishing these operations at Centrus’ existing Ohio site, the companies intend to create an integrated hub that co-locates enrichment and deconversion to improve efficiency and reduce costs for the advanced nuclear industry. The partnership seeks to address a significant bottleneck in the US nuclear supply chain by expanding domestic capacity for advanced reactor fuels. Currently, various HALEU-fueled technologies are under development, and a centralized deconversion hub could eliminate the need for individual fuel fabrication plants to maintain their own separate lines.

This move is expected to simplify logistics, lower shipping costs, and enhance the overall competitiveness of the US nuclear sector as it moves toward large-scale deployment. Beyond technical operations, Oklo Inc. (NYSE:OKLO) and Centrus plan to coordinate on regulatory and research activities, including engagement with federal and local agencies to support the infrastructure in Pike County. This initiative aligns with broader regional redevelopment efforts led by the Southern Ohio Diversification Initiative to transform the former Portsmouth Gaseous Diffusion Plant into a clean energy center.

Oklo Inc. (NYSE:OKLO) develops advanced fission power plants to provide clean, reliable, and affordable energy at scale to customers in the US, specifically targeting the high power demands of AI data centers. It also commercializes nuclear fuel recycling tech that converts nuclear waste into usable fuel for its reactors.

While we acknowledge the potential of OKLO as an investment, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an extremely cheap AI stock that is also a major beneficiary of Trump tariffs and onshoring, see our free report on the best short-term AI stock.

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